marți, 24 ianuarie 2017

Heat shock proteins and shell shock

I was always intrigued by the fact that a temporary trauma as the shell shock (or post traumatic stress disorder) can have long term effects on the human psyche.
I was viewing this lecture in heat shock proteins and the effect of the stress on them, and I was wondering what effects on the psyche the quantity of heat shock proteins can have.
A mild stress on the cell increases quantity of heat shock proteins, protecting in this way correct folding of proteins and functioning of the cell.
A high stress however depletes the reserve of heat shock proteins and the functioning of the cell is more affected by the genetic factors.
For example lets suppose that you have vulnerability for an organic psychiatric disease but due to heat shock proteins your neurons are working normal in a normal environment, but if you receive a shock like an aggression or a drug consumption, the heat shock proteins are depleted, and your neurons are working chaotically and you start to have delusions.

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